Systems Biology Laboratory

News

New research shows the critical role of lymphatic vessels in cancer and metastasis

http://www.nature.com/ncomms/2014/140902/ncomms5715/full/ncomms5715.html
Sept 2, 2014 'Prepped' by tumor cells, lymphatic cells encourage breast cancer cells to spread. HIV drug plus blood vessel growth-blockers could halt metastasis. http://www.eurekalert.org/pub_releases/2014-09/jhm-btf090214.php

Johns Hopkins researchers discover that an FDA-approved HIV drug may be useful in treating breast cancer metastasis. http://www.bme.jhu.edu/news-events/news-highlights.php?id=455

http://www.sciencedaily.com/releases/2014/09/140902171146.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fpharmaceuticals+(Pharmaceuticals+News+--+ScienceDaily)

Sept 3, 2014 Tumor Cells May Encourage Lymphatic Cells to Spread Breast Cancer - And a New Treatment Could Stop It. http://oncozine.com/profiles/blogs/tumor-cells-may-encourage-lymphatic-cells-to-spread-breast-cancer

Breast Cancer News http://breastcancer-news.com/2014/09/03/breast-cancer-cells-promote-metastasis-lymphatic-cells/

Sept 3, 2014 GEN Genetic Engineering & Biotechnology News. Lymphatic Cells Shill for Breast Cancer. http://www.genengnews.com/gen-news-highlights/lymphatic-cells-shill-for-breast-cancer/81250302/

‘PREPPED’ BY TUMOR CELLS, LYMPHATIC CELLS ENCOURAGE BREAST CANCER CELLS TO SPREAD. http://utopiantreasures.com/theopenmind

http://medicalxpress.com/news/2014-09-prepped-tumor-cells-lymphatic-breast.html

http://www.newswise.com/articles/view/622708/?sc=rsla&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+NewswiseLatestNews+%28Newswise%3A+Latest+News%29

Sept 6, 2014 http://www.medindia.net/news/lymphatic-cells-encourage-breast-cancer-cells-to-spread-140967-1.htm

http://bmes.org/blog_home.asp?Display=178

 

Cover Page in Microvascular Research for the entire year 2014

Hispanic Business.com (October 25, 2013)

“Researchers from Johns Hopkins University School of Medicine Report on Findings in Angiogenesis”

http://www.hispanicbusiness.com/2013/10/16/researchers_from_johns_hopkins_university_school.htm

Highlights in The Washington Post (October 4, 2013)

“Collaboration with the Johns Hopkins Carey Business School and the Discovery to Market technology transfer course on developing treatments for AMD”

http://www.washingtonpost.com/wp-adv/units/22029-fall-grad-guide-refresh/01-learning-cover.html

Treatment of central vision loss (September 6, 2013)

“BME researchers testing promising drug therapy delivery method for improved treatment of central vision loss"

http://www.bme.jhu.edu/news-events/news-highlights.php?id=396

Drug Deliver Pharmaceutical (August 22, 2013)

“Johns Hopkins’ biomedical engineers to create therapeutic eye injections”

http://drugdelivery.pharmaceutical-business-review.com/news/johns-hopkins-biomedical-engineers-to-create-therapeutic-eye-injections-220813\

Hispanic Business.com (August 21, 2013)

“Time-release coating allows drug for macular degeneration to last longer” http://www.hispanicbusiness.com/2013/8/21/johns_hopkins_-_therapeutic_eye_injections.htm

FierceDrugDelivery (August 20, 2013)

“Time-release delivery of vision-loss drug demands fewer injections.”

http://www.fiercedrugdelivery.com/story/time-release-delivery-vision-loss-drug-demands-fewer-injections/2013-08-20#ixzz2d8eyttzp

Hopkins Medicine (August 19, 2013)

“Therapeutic eye injections may be needed less often” http://www.hopkinsmedicine.org/news/media/releases/therapeutic_eye_injections_may_be_needed_less_often

http://www.sciencenewsline.com/articles/2013081914460006.htm

http://medicalxpress.com/news/2013-08-therapeutic-eye.html

Our lab work was featured in the article "Creating accurate models of life" in IEEE pulse, March/April 2013

”In my opinion, computational systems biology, including multiscale modeling, will be at the forefront of the transformation of medicine, a process that has just begun,” commented by Dr. Aleksander S. Popel. Stacey Finley and Lawrence Chu's work contributes Fig. S1 and S2, respectively. pdf dowload

Kerri-Ann Norton was awarded an American Cancer Society Postdoctoral Fellowship

She received this award for the topic "Computational Modeling of Tumor-Induced Angiogenesis". Congratulations!

http://www.cancer.org/research/applyforaresearchgrant/granttypes/postdoctoral-fellowships

Spyros Stamatelos selected to receive 2013 MCS John R. Pappenheimer Postdoctoral Travel Award

November 2012 Special Issue: Multiscale Systems Biology Cover: Schematic illustrating “multiscale” imaging of the angiogenic phenotype. From: Eugene Kim, Spyros Stamatelos, Jana Cebulla, Zaver M. Bhujwalla, Aleksander S. Popel, and Arvind P. Pathak.

spyros_cover_2012

Spyros Stamatelos honored at INBT research symposium

http://psoc.inbt.jhu.edu/2012/05/16/four-students-honored-at-inbt-research-symposium/

Spyros Stamatelos was first author with Eugene Kim, Arvind Pathak and Aleksander Popel on the poster Characterization of the Heterogeneity of Tumor Vasculature using Hemodynamic Modeling and High Resolution Imaging Implications for Drug Delivery.

Esak Lee honored at 5th Annual Safeway Breast Cancer Retreat, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University

"Runner Up" Poster Award was presented to Esak Lee who was first author with Niranjan Pandey and Aleksander Popel on the poster titled "Lymphatic endothelial cells (LEC) induce angiogenesis in axillary and brachial lymph nodes in breast cancer."

Stacey Finley selected to receive conference travel award

A travel award was presented to Stacey Finley to attend the SIAM (Society of Industrial and Applied Mathematics) Life Sciences Conference in San Diego, August 7-10, 2012. Stacey will give an oral presentation entitled "Multiscale modeling of breast cancer angiogenesis with therapeutic applications". Dr. Aleksander Popel is senior author on the abstract.

Practical Applications of Systems Biology Approach Provides New Perspectives for Biomedical Science Research Initiatives

Genetic Engineering & Biotechnology News, May 1, 2009. Click here for more information

A couple of press items on our paper in PNAS, see below:

from Pharmaceutical Executive: Click here
from Johns Hopkins Newsletter: Click here

 

Three journal covers from our recent papers:

Physiological Genomics, June 6, 2009, Click here for more information

Nitric Oxide, Volume 20, Issue 4, 2008, click here for more information

Antioxidants and Redox Signaling, Volume 10,Number 7, 2008, Click here for more information.