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Review Articles: 7. Nihongaki Y. "Dynamic molecular mechanism of primary cilia disassembly" Experimental Medicine [in Japanese] (2018) 6. Niu J., Ben Johny M., Dick I.E., Inoue T. "Following Optogenetic Dimerizers and Quantitative Prospects" Biophysical Journal (2016) PDF 5. Kim A.K., DeRose R., Ueno T., Lin B., Komatsu T., Nakamura H., Inoue T. "Toward total synthesis of cell function: Reconstituting cell dynamics with synthetic biology" Science Signaling (2016) PDF 4. Phua S., Lin Y., Inoue T. "An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli" Cell Calcium (2015) PDF 3. Lin Y.C., Phua S.C., Lin B.,, and Inoue T., "Visulaizing molecular diffusion through passive permeability barriers in cells: conventional and novel approaches" Curr. Opin. Chem Bio (2013) PDF 2. DeRose
R. Miyamoto T. and Inoue T., “Manipulating signaling at will:
chemically-inducible dimerization 1.
Miyamoto T., Razavi S., DeRose R., and Inoue T. “Synthesizing
Biomolecule-based Boolean Logic Gates” (In press) ACS Synthetic
Biology PDF Editorial Articles: 3. Inoue T. "A hair of cells that is old but new, and small but big" Experimental Medicine [in Japanese] (2018) 2. Gaus K., Inoue T. "New Biological Frontiers Illuminated by Molecular Sensors and Actuators" Biophysical Journal (2016) PDF 1. Miyamoto T., Rho E., and Inoue T.* “Deconvoluting
AMPK Signaling” Oncotarget
(In press)
Research Articles: 41. Nakamura H., Lee A.A., Sobhi Afshar A., Watanabe S., Rho E., Razavi S., Suarez A., Lin Y.C., Tanigawa M., Huang B., DeRose R., Bobb D., Hong W., Gabelli S.B., Goutsias J., Inoue T. "Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions" Nature Materials Advance Online Publication (2017) PDF 40. Phua S.C., Chiba S., Suzuki M., Su E., Roberson E.C., Pusapati G.V., Setou M., Rohatgi R., Reiter J.F., Ikegami K., Inoue T. "Dynamic Remodeling of Membrane Composition Drives Cell Cycles through Primary Celia Excision" Cell 168(1-2):264-279 (2017) PDF 39. Meier E.L., Razavi S., Inoue T., Goley E.D. "A Novel membrane anchor for FtsZ linked to cell wall hydrolysis in Caulobacter crescentus" Molecular Microbiology 101(2):265-80 (2016) PDF 38.
Nguyen H-N., Miyamoto T., Yang, J-M., Inoue T., Sesaki H., Devreotes
P.N., and Iijima M. “Opening the conformation is a master switch for
the dual localization and phosphatase activity of PTEN” Scientific
Reports 5, 12600 (2015) PDF 37. Garcia-Gonzalo F.R., Phua S.C., Roberson E.C., Galo
Garcia
III, Abedin M., Schurmans S., Inoue T.*, Jeremy F. Reiter*
“Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate
Hedgehog Signaling” Developmental
Cell 34, 400-409 (2015) PDF 36.
Antonczak A.K., Mullee L., Wang Y., Comartin D., Inoue T., Pelletier L.
and Morrison C.G. "Opposing effects of pericentrin and microcephalin on
the pericentriolar material regulate CHK1 activation in the DNA damage
response" (in press, Oncogene)
PDF 35.
Miyamoto T., Rho E., Sample V., Akano H., Magari M., Ueno T., Gorshkov
K., Chen M., Tokumitsu H., Zhang J., and Inoue T.* "Compartmentalized
AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and
Actuators" Cell
Reports 11, 657-670 (2015) PDF 34.
Lin B., Yin T., Wu Y., Inoue T., and Levchenko A. "Interplay between
chemotaxis and contact inhibition of locomotion determines exploratory
cell migration" Nature
Communications (2015) PDF 33. Adams P.J., Johny M.B., Dick I.E., Inoue T., and Yue D.T., "Apocalmodulin itself promotes ion channel opening and Ca regulation" Cell 159(3), 608-622 (2014) PDF 32. Razavi S., Su S., and Inoue T. "Cellular Signaling Circuits Interfaced with Synthetic, Post-Translational, Negating Boolean Logic Devices" ACS Synthetic Biology (2014) PDF 31. Onuma H., Komatsu T., Arita M., Hanaoka K., Ueno T., Terai T., Nagano T., and Inoue T. "Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation" Science Signaling (2014) PDF 30. Suarez A., Ueno T., Huebner R., McCaffery J.M., and Inoue T. "Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells" Scientific Reports (2014) PDF 29. Kobayashi T., Kim S., Lin Y.C., Inoue T., and Dynlacht B.D. "The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly" J. Cell Biol. (2014) PDF 28. Su S.*, Phua S.C.*, DeRose R., Chiba S., Narita K., Kalugin P.N., Katada T., Kontani K., Takeda S., and Inoue T. "Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia" Nature Methods (2013) PDF 27. Thevathasan, J.V., Tan E., Hui Z., Lin Y.C., Li Y., Inoue T. and Fivaz M. “Local positive feedback from PI3K to Ras drives cell polarization and migration” Molecular Biology of the Cell (in press) 26. Y.C. Lin, P. Niewiadomski, B. Lin, H. Nakamura, S.C. Phua, J. Jiao, A. Levchenko, T. Inoue, R. Rohatgi, and T. Inoue “Chemically-inducible diffusion trap reveals molecular sieve-like barrier at primary cilia“ Nature Chemical Biology PDF 25. Lin YC, Nihongaki Y, Liu T-Y, Razavi S, Sato M, and Inoue T. “Rapidly Reversible Manipulation of Molecular Activities Using Dual Chemical Dimerizers” Angewandte Chemie PDF 24.
Lin B., Wang J., Ueno T., Harwell A., Inoue T.* and Levchenko A.*
“Synthetic spatially graded Rac activation drives directed cell
polarization and locomotion“ PNAS
109, E3668 (2012) PDF 23. Sample V., Ni Q., Inoue T. and Zhang J. “Controlling Enzymatic Action in Living Cells with a Kinase-dependent Bimolecular Switch” ACS Chemical Biology PDF 22. Phua S.C., Pohlmeyer C., and Inoue T. "Rapdily
Relocating Molecules Between Organelles to Manipulate Small GTPase
Activity" ACS
Chemical Biology (2012) PDF 21.
Miyamoto T.*, DeRose R.*, Suarez A., Ueno T., Chen M., Sun T., Wolfgang
M., Mukherjee C., Meyers D., and Inoue T.“Rapid and Orthogonal Logic
Gating with a Novel Gibberellin-Induced Dimerization System” Nature Chemical Biology (2012) PDF 20.
DeRose R.*, Pohlmeyer C.*, Umeda N.*, Ueno T., Nagano T., Kuo S., and
Inoue T. “Moving molecules by light; Spatio-temporal manipulation of
small GTPase activity at subcellular level and on timescale of seconds
in living cells” Journal of
Visualized Experiments (2012) VIDEO 19.
Ueno T., Falkenburger B.H., Pohlmeyer C., and Inoue T.“Triggering Actin
Comets Versus Membrane Ruffles: Distinctive Effects of
Phosphoinositides on Actin Reorganization” Science
Signaling 4(203), ra87 (2011) PDF 18. Komatsu T., Johnsson K., Okuno H., Bito H., Inoue T., Nagano T. and Urano Y. “Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling (FAPL) method” Journal of American Chemical Society 133, 6745-6751 (2011) PDF 17.
Umeda N.*, Ueno T* Pohlmeyer C., Nagano T. and Inoue T. “A
photocleavable rapamycin conjugate for spatiotemporal control of small
GTPase activity” Journal of American
Chemical Society 133(1), 12-14 (2011) PDF 16.
Komatsu T.*, Kukelyansky I.*, McCaffery J.M., Ueno T., Varela L.C. and
Inoue T. “Organelle-Specific, Rapid Induction of Molecular Activities
and Membrane Tethering” Nature Methods
7, 206-208 (2010) PDF 15. Rahdar M., Inoue T., Meyer T., Zhang J., Vazquez F., and Devreotes P.N. “A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN” Proc. Natl. Acad. Sci. U S A. 106(2):480-5 (2009) PDF 14. Inoue T. and Meyer T. “Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration” PLoS ONE 3(8), e3068 (2008) PDF 13. Yogo T., Urano Y., Mizushima A., Sunahara H., Inoue T., Hirose K., Iino M., Kikuchi K., and Nagano T. "Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer" Proc. Natl. Acad. Sci. U S A. 105, 28-32 (2008) PDF 12. Fivaz M., Bandara S., Inoue T. and Meyer T. "Robust neuronal symmetry breaking by Ras-triggered local positive feedback" Current Biology 18, 44-50 (2008) PDF 11. Abe N., Klein L., Inoue T., Galvez T., and Meyer T. “Dissecting the role of PI(4,5)P2 in transferrin receptor endocytosis and recycling” Journal of Cell Science 121, 1488 (2008) PDF 10. Aoki. K, Nakamura T, Inoue T, Meyer T, and Matsuda M. “An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor–stimulated PC12 cells” Journal of Cell Biology 177, 817-827 (2007) PDF 9.
Liou J, Fivaz M, Inoue T, and Meyer T. “Live-cell imaging reveals
sequential oligomerization and local PM targeting of STIM1 following
Ca2+ store depletion” Proc. Natl.
Acad. Sci. U S A. 104, 9301-9306 (2007) 8. Suh BC*, Inoue T*, Meyer T, and Hille B. “Rapid
chemically-induced changes of PtdIns(4,5)P2 gate KCNQ ion channels” Science 314, 1454-1457 (2006) (*Contributed Equally) 7. Heo WD, Inoue T, Park WS, Kim ML, Park BO, Wandless TJ, and Meyer T. “PI(3,4,5)P3 and PI(4,5)P2 lipids target Ras, Rho, Arf and Rab GTPases to the plasma membrane” Science 314, 1458-1461 (2006) PDF 6. Inoue T, Heo WD, Grimley JS, Wandless TJ, and Meyer T. “Inducible translocation strategies to rapidly activate and inhibit small GTPase signaling pathways” Nature Methods 2, 415-418 (2005) PDF 5. Yogo T, Kikuchi K, Inoue T, Hirose K, Iino M, and Nagano T. “Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.” Chem. Biol. 11, 1053-1058 (2004) PDF 4.
Inoue T, Kikuchi K, Hirose K, Iino M, and Nagano T. “Spatiotemporal
Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptors Using
Synthetic Small-molecule Probes” Chem.
Biol. 10, 503-509 (2003) 3. Nakanishi W, Kikuchi K, Inoue T, Hirose K, Iino M, and Nagano T. “Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor binding” Bioorg. Med. Chem. Lett. 12, 911-913 (2002) PDF 2. Inoue T, Kikuchi K, Hirose K, Iino M, and Nagano T. “Small molecule-based laser inactivation of inositol 1,4,5-trisphosphate receptor” Chem. Biol. 8, 9-15 (2001) PDF 1.
Inoue T, Kikuchi K, Hirose K, Iino M, and Nagano T. “Synthesis and
evaluation of 1-position-modified inositol 1,4,5-trisphosphate analogs” Bioorg. Med. Chem. Lett. 9,
1697-1702 (1999) PDF
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