| September 1985 |
Funding awarded by the National Eye Institute |
| November 1986 |
First patient randomized in large tumor trial |
| January 1987 |
First patient randomized in medium tumor trial |
| December 1994 |
Patient enrollment of large tumor trial completed |
| June 1998 |
Initial survival data from large tumor trial published |
| July 1998 |
Patient enrollment in medium tumor trial completed |
| July 2000 |
Clinical patient follow-up in large tumor trial completed |
| July 2001 |
Initial survival data from medium tumor trial published |
| July 2003 |
Clinical patient follow-up in medium tumor trial completed |
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