Synthetic Cell Biology

Our research focuses on “synthetic cell biology” to dissect and reconstitute intricate signaling networks. In particular, we investigate positive-feedback mechanisms underlying the initiation of neutrophil chemotaxis (known as a symmetry breaking process), as well as spatio-temporally dynamic information processing at various compartments in living cells. In parallel, our lab also tries to understand how cell morphology affects biochemical functions. Ultimately, we will generate completely orthogonal nano-machinery in artificial cells that can achieve existing, and even novel, cellular functions. Our research is conducted in an open lab style building which embodies multidisciplinary research. Students who are enthusiastic about learning diverse disciplines, developing innovative techniques, and challenging fundamental biological problems would enjoy the environment. We welcome students to our lab for discussions about potential research projects.