Purpose of the COMS
The Collaborative Ocular Melanoma Study (COMS) is a multicenter investigation designed to evaluate therapeutic interventions for patients who have choroidal melanoma. Evaluations conducted in the COMS are aimed at determining which of two alternative therapies better prolongs the remaining lifetime of individuals diagnosed as having choroidal melanoma and, if two alternatives provide similar expectations of survival, to determine which offers the patient the longer cancer-free life and the better prognosis for vision overall. Currently, two randomized controlled trials are being conducted as separate substudies:
In addition to the two randomized trials, a number of pilot studies and ancillary studies have been and continue to be conducted by COMS investigators.
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